LEISHMANIA-IgG ELISA DOG (1 ELISA plate)

The LEISHMANIA IgG ELISA DOG is an Enzyme Immunoassay for detecting IgG antibodies to Leishmania infantum in serum and plasma samples from dogs.

Leishmania infantum is the causative agent of leishmaniasis - an important zoonoses which occurs particulary in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe. Dogs are the main reservoir host and the disease is potentially fatal in dogs and people. Spread by the bite of infected sandflies, dogs of all ages can be infected and the incubation period can range from months to years.

The disease can proceed symptomatically (accompanied by polyclonal B-cell-activation; generation of specific antibodies and cellular immunosuppression), subclinically (accompanied by specific humoral immune response) or latently (lack of respectively very weak humoral and protective cellular immune response). Clinical symptoms are (ordered by decreasing frequency) lymphadenopathy, skin reactions, cachexia, hyperthermia, conjunctivitis, splenomegalia and abnormal claws. Often slight to moderately normochromic anemia, moderate leukopenia, hypergammaglobulinemia and hypoalbuminemia are observed.

Features and benefits

• Reliable test for detection of leishmaniasis in dogs
• High sensitivity of up to 88.4% and high specificity of up to 99.5% 
  (validated with n = 50 characterized dog sera)
  
  

Improve your workflow efficiency with AFOSA assays

• Ready-to-use reagents (Positive/Negative Controls, Conjugate, Substrate, Stop Solution)
• Color-coded caps
  Interchangeable reagents between AFOSA assays
• Microplate with 12 individual strips of 8 wells
• Suitable for automated ELISA instruments